Are you interested in how our products can improve your clinic's effectiveness, save you time and help you treat more patients? Book a demo

Cosylab Logo Cosylab Logo
  • Solutions
    BIG SCIENCE
    • Particle Accelerators
    • Fusion Energy
    • Astronomy
    RADIATION ONCOLOGY
    • Radiation Therapy
    HIGH TECH & INDUSTRIAL
    • Quantum Systems
    • Semiconductor
    • Space
  • Products
    • PLANONE™
    • starQ Controller
  • Resources
    • Customer stories
    • Blog
    • Expertise
  • News & events
  • About
    • About us
    • Leadership team
    • Careers
    • Contact us
Book a meeting
  • sl
  • en
  • zh
  • ja
Book a meeting
  • sl
  • en
  • zh
  • ja
View all results

PLANONE™ BY COSYLAB

Treatment Planning System Built for Particle Therapy

Native GPU-accelerated Monte Carlo, transparent physics and radiobiology, and a unified clinical workflow come together in a single environment for contouring, planning, and review.

Developed by Cosylab, it is designed to support the future of particle therapy as workflows, machines, and modalities evolve.
Request a demo Talk to our team
The challenge

Particle therapy is outpacing the planning tools

Clinical ambition in particle therapy programs has moved past what conventional planning algorithms were designed to do.

Physics Accuracy

Research is moving beyond dose and LET, but many planning workflows have not.

Radiobiological Complexity

Growing interest in variable RBE is increasing the need for biological evaluation in treatment planning.

Workflow Fragmentation

Disconnected planning workflows create unnecessary complexity and inefficiency.

Institutional Risk

Clinics cannot afford to replace trusted systems or disrupt established workflows.

Future readiness

As automation, adaptive therapy, and AI advance, planning systems must keep pace with changing clinical requirements

Request a PlanOne™ Demo

Are you interested in how our products can improve your clinic's effectiveness, save you time and help you treat more patients?

Book a demo
What PlanOne™ Delivers as a Treatment Planning System

Clinical precision and workflow

In particle therapy, physical dose, LET, and radiobiological dose are closely linked. Planning now often demands a comprehensive understanding of all three. PlanOne™ was designed with this in mind: it features a Monte Carlo engine that directly generates the LET distribution, an RBE workflow that utilizes this data, and a clinical setting where contouring, planning, and review are seamlessly integrated within the same application.

Physics & Radiobiology, hand in hand

  • GPU-accelerated Monte Carlo for particle therapy*.
  • LET optimization and visualization.
  • Variable RBE — MCF-MKM, Linear LET weighted*.
  • Direct access to macro- and microdosimetric quantities, supporting advanced radiobiological modelling and evaluation.
  • User-defined robust optimization, analysis & evaluation*.

Workflow & connectivity

  • Unified workflow environment.
  • Particle planning tools.
  • Advanced Spot Editor*.
  • GPU-accelerated computation.
  • Scripting API.
  • OIS Connectivity.
  • Direct machine connectivity via the Treatment Workspace*.
Designed to evolve with planning workflows

A platform designed for the adaptive and AI era

Automation is already integral to modern treatment planning. PlanOne™ is designed to support increasingly advanced workflows, from scripting and workflow automation to AI-assisted contouring, dose forecasting, and planning.
"Our partners have been clear on what matters most for particle therapy: physics accuracy they can defend, clinical confidence at the point of plan approval, and a platform built to grow with AI and adaptive workflows. We designed PlanOne™ around those three priorities, and we'll keep developing it together with the clinical community that helped shape it."

Mark Pleško

CEO of Cosylab

Built by Cosylab

Two decades of building the systems behind the world’s most demanding science

From particle accelerators and radiation therapy systems to fusion experiments and engineering test facilities, Cosylab develops software for environments where precision matters. More than 1,000 projects delivered.

Request a PlanOne™ Demo at PTCOG 64

Schedule a 30-minute discovery session with our medical physics team. We'll walk through biological dose optimization, AI-assisted planning workflows, and adaptive radiotherapy capabilities specific to your center's needs, whether you're planning a new facility or upgrading existing systems.

Book a demo
LATEST UPDATES

PlanOne News & Developments

Stay informed about PlanOne's development milestones, clinical partnerships, and upcoming presentations at major radiation therapy conferences.

UPCOMING CONFERENCE

PlanOne™ to be Presented at PTCOG 2026

Join us at the Particle Therapy Co-Operative Group conference in June 2026 to see PlanOne™ demonstrations and learn about biological dose optimization for proton therapy.

June 8, 2026 | Deauville, France

PlanOne™ to be Presented at PTCOG 2026
View All PlanOne Updates

Deauville, France 8-13 June 2026

Request a PlanOne™ Demo at PTCOG 64

Are you interested in how our products can improve your clinic's effectiveness, save you time and help you treat more patients?

PlanOne™ V1.0 is FDA 510(k) cleared. Items marked with * are in preparation for regulatory submission or under development; not yet available for sale and/or clinical use in any market. Market availability is subject to regulatory approval. PlanOne is a trademark of Cosylab d.d., registered in the United States and the European Union.

The leading provider of cutting-edge expertise, software and electronics for the world’s most advanced systems and devices.

Our expertise
  • Expertise
Solutions
  • Radiation therapy
    • Manufacturers
    • Clinics
  • Complex medical solutions
  • Quantum
    • starQ Controller
  • Accelerators
  • Fusion
  • Space
  • Astronomy
Media
  • Blog
  • News & events
About
  • Contact
  • About us
  • Careers
  • linkedin
  • facebook
  • instagram
  • twitter
  • Privacy policy

© 2026 Cosylab. All rights reserved.